Description

1H-2-Benzazepin-8-Ol, 2,3,4,5-Tetrahydro-, Hydrobromide is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical pharmacological intermediate and building block for research into novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel benzazepine-based drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as an analytical standard for quality control and method development in API (Active Pharmaceutical Ingredient) manufacturing.
• Biochemical Research: Investigated for its potential interactions with specific receptor subtypes in pharmacological assays.
• Process Chemistry Development: Utilized in scaling up synthetic routes for potential new chemical entities (NCEs).
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	1H-2-Benzazepin-8-Ol, 2,3,4,5-Tetrahydro-, Hydrobromide
CAS No.	374813-35-1
Molecular Formula	C10H14BrNO
Molecular Weight	244.13 g/mol
Synonyms	2,3,4,5-Tetrahydro-1H-2-benzazepin-8-ol hydrobromide; 8-Hydroxy-2,3,4,5-tetrahydro-1H-2-benzazepine hydrobromide; 1H-2-Benzazepin-8-ol, 2,3,4,5-tetrahydro-, hydrobromide (1:1); Tetrahydrobenzazepinol hydrobromide; BRN 8510141; SCHEMBL23833079; AKOS025147065; ZINC000004055756
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested to ensure identity, purity, and consistency, supporting reliable outcomes in critical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.