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1-Acetyl-5-Bromo-3-(4-Oxo-2-[3-(Trifluoromethyl)Anilino]-1,3-Thiazol-5(4H)-Ylidene)-1,3-Dihydro-2H-Indol-2-One CAS NO 374768-12-4


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CAS No.:374768-12-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Acetyl-5-Bromo-3-(4-Oxo-2-[3-(Trifluoromethyl)Anilino]-1,3-Thiazol-5(4H)-Ylidene)-1,3-Dihydro-2H-Indol-2-One is a sophisticated heterocyclic organic compound featuring a complex indole-thiazolidinone hybrid structure, designed for advanced chemical synthesis. This high-value intermediate is critical for research and development in pharmaceutical chemistry, particularly in the discovery of novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting specific enzyme receptors.
  • Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its unique heterocyclic core.
  • Chemical Biology Probe: Acts as a scaffold for creating molecular probes to study biological pathways and protein interactions.
  • Material Science Research: Investigated as a precursor for advanced organic electronic materials due to its conjugated system.
  • Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic organic chemistry projects.
  • Custom Synthesis: Employed by fine chemical manufacturers for the bespoke production of complex molecules for client-specific applications.

Basic Information

Product Name 1-Acetyl-5-Bromo-3-(4-Oxo-2-[3-(Trifluoromethyl)Anilino]-1,3-Thiazol-5(4H)-Ylidene)-1,3-Dihydro-2H-Indol-2-One
CAS No. 374768-12-4
Molecular Formula C20H11BrF3N3O2S
Molecular Weight 502.29 g/mol
Synonyms 5-Bromo-1-acetyl-3-[(2-{[3-(trifluoromethyl)phenyl]amino}-4-oxo-1,3-thiazol-5(4H)-ylidene)methyl]-1H-indol-2(3H)-one; 1-Acetyl-5-bromo-3-[(2-{[3-(trifluoromethyl)phenyl]amino}-4-oxo-1,3-thiazolidin-5-ylidene)methyl]indolin-2-one; 374768-12-4; 5-Bromo-1-acetyl-3-((2-((3-(trifluoromethyl)phenyl)amino)-4-oxothiazol-5(4H)-ylidene)methyl)indolin-2-one; Indole-thiazolidinone hybrid derivative; Trifluoromethylanilino thiazolylidene indolone
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Quality Control

Our 1-Acetyl-5-Bromo-3-(4-Oxo-2-[3-(Trifluoromethyl)Anilino]-1,3-Thiazol-5(4H)-Ylidene)-1,3-Dihydro-2H-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, and our quality protocols are designed to meet the stringent requirements of global R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance Yellow to orange crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95% (Area %)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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