Description

7-Amino-5-Bromoindole is a high-purity, versatile brominated indole derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and bromo substituents, makes it an essential intermediate for constructing complex heterocyclic compounds. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors, serotonin receptor modulators, and other bioactive molecules targeting central nervous system disorders.
• Agrochemical Research: Used to develop novel fungicides and herbicides by acting as a core scaffold for new active ingredients with enhanced efficacy.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic semiconductors, conductive polymers, and advanced photoresists.
• Chemical Biology & Proteomics: Employed as a versatile tag or linker molecule for bioconjugation and probe development in biochemical assays.
• Dye & Pigment Synthesis: Acts as an intermediate for producing specialized indole-based dyes and colorants with specific light-absorption properties.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	7-Amino-5-Bromoindole
CAS No.	374537-99-2
Molecular Formula	C8H7BrN2
Molecular Weight	211.06 g/mol
Synonyms	5-Bromo-1H-indol-7-amine; 5-Bromo-7-aminoindole; 1H-Indol-7-amine, 5-bromo-; 7-Amino-5-bromo-1H-indole; 5-Bromo-7-indolamine
EINECS	Contact for details

Quality Control

Our 7-Amino-5-Bromoindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.