Description

4-Chloro-5-p-Tolyl-Thieno[2,3-D]Pyrimidine is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, where its unique fused-ring structure provides a versatile scaffold for further functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in creating new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Potential intermediate for creating organic electronic materials, such as semiconductors or light-emitting compounds, due to its conjugated thienopyrimidine core.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploration of new heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-5-p-Tolyl-Thieno[2,3-D]Pyrimidine
CAS No.	374104-63-9
Molecular Formula	C₁₃H₉ClN₂S
Molecular Weight	260.74 g/mol
Synonyms	4-Chloro-5-(4-methylphenyl)thieno[2,3-d]pyrimidine; 5-(4-Methylphenyl)-4-chlorothieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 4-chloro-5-(4-methylphenyl)-; 4-Chloro-5-(p-tolyl)thieno[2,3-d]pyrimidine; 4-Chloro-5-(4-tolyl)thieno[2,3-d]pyrimidine; 374104-63-9; 4-Chloro-5-(4-methylphenyl)-thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-p-Tolyl-Thieno[2,3-D]Pyrimidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.