Description

(5E)-1-(3-Fluorophenyl)-5-[(1-Methyl-1H-Indol-3-Yl)Methylidene]-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione is a sophisticated heterocyclic compound featuring a unique molecular scaffold that combines indole and dihydropyrimidine-dione pharmacophores. This structure is of significant interest for its potential as a key pharmaceutical intermediate or a biological research probe in medicinal chemistry programs. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of new chemical entities (NCEs) for drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for developing modulators of specific biological targets, such as enzymes or receptors.
• Chemical Biology Probe: Employed in biochemical and cellular assays to study protein function and signaling pathways.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, high-value specialty chemicals for advanced applications.
• Academic Research: A valuable compound for universities and research institutes conducting studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(5E)-1-(3-Fluorophenyl)-5-[(1-Methyl-1H-Indol-3-Yl)Methylidene]-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione
CAS No.	373374-67-5
Molecular Formula	C20H14FN3O2S
Molecular Weight	379.41 g/mol
Synonyms	1-(3-Fluorophenyl)-5-[(1-methyl-1H-indol-3-yl)methylene]-2-thioxo-1,3-diazinane-4,6-dione; 5-[(1-Methylindol-3-yl)methylene]-1-(3-fluorophenyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; (5E)-1-(3-Fluorophenyl)-5-(1-methyl-1H-indol-3-ylmethylene)-2-thioxohexahydropyrimidine-4,6-dione; 373374-67-5; 5-((1-Methyl-1H-indol-3-yl)methylene)-1-(3-fluorophenyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, and we can support custom purity requirements for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.