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6-Methylpyridine-2-Boronic Acid CAS NO 372963-50-3


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CAS No.:372963-50-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Methylpyridine-2-Boronic Acid is a versatile boronic acid derivative and a key building block in modern synthetic chemistry. Its primary value lies in its role as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active ingredients, functional ligands, and novel chemical entities.

Application

  • Pharmaceutical Intermediate: A critical reagent for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine scaffolds.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
  • Material Science: Serves as a building block for creating organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
  • Catalyst & Ligand Development: Employed in the design and synthesis of novel catalysts and chiral ligands for asymmetric synthesis.
  • Chemical Research: A fundamental tool in academic and industrial R&D for exploring new carbon-carbon bond-forming methodologies and library synthesis.
  • Diagnostic Reagents: Potential use in the development of biochemical probes and sensor materials due to its boronic acid functionality.

Basic Information

Product Name 6-Methylpyridine-2-Boronic Acid
CAS No. 372963-50-3
Molecular Formula C6H8BNO2
Molecular Weight 136.95 g/mol
Synonyms (6-Methylpyridin-2-yl)boronic Acid; 2-Borono-6-picoline; 6-Methyl-2-pyridineboronic Acid; 6-Methylpyridine-2-boronic Acid Pinacol Ester (common precursor); 2-(6-Methylpyridyl)boronic Acid; 6-Methyl-2-pyridinylboronic Acid; 2-Pyridineboronic Acid, 6-methyl-; B-(6-Methyl-2-pyridinyl)boronic Acid
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Quality Control

Our 6-Methylpyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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