Description

1-Isopropyl-3-Oxo-2,3,5,6,7,8-Hexahydroisoquinoline-4-Carbonitrile is a high-value, nitrogen-containing heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique fused-ring structure and functional groups make it a versatile building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical development companies for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex polycyclic frameworks and functionalized isoquinoline derivatives.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or functional materials due to its nitrile and carbonyl groups.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	1-Isopropyl-3-Oxo-2,3,5,6,7,8-Hexahydroisoquinoline-4-Carbonitrile
CAS No.	371930-42-6
Molecular Formula	C₁₃H₁₆N₂O
Molecular Weight	216.28 g/mol
Synonyms	4-Cyano-1-isopropyl-2,3,5,6,7,8-hexahydroisoquinolin-3-one; 1-Isopropyl-3-oxo-2,3,5,6,7,8-hexahydro-4-isoquinolinecarbonitrile; 1-Propan-2-yl-3-oxo-2,5,6,7,8-hexahydroisoquinoline-4-carbonitrile; 3-Oxo-1-isopropyl-2,3,5,6,7,8-hexahydroisoquinoline-4-carbonitrile; 1-Isopropyl-3-oxo-1,2,5,6,7,8-hexahydroisoquinoline-4-carbonitrile; 1-(1-Methylethyl)-3-oxo-2,3,5,6,7,8-hexahydro-4-isoquinolinecarbonitrile; CAS 371930-42-6
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-3-Oxo-2,3,5,6,7,8-Hexahydroisoquinoline-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.