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2-[(1-Benzyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)Methyl]-3-(2-Methoxyphenyl)-4(3H)-Quinazolinone CAS NO 371782-40-0


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CAS No.:371782-40-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[(1-Benzyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)Methyl]-3-(2-Methoxyphenyl)-4(3H)-Quinazolinone is a high-purity, complex heterocyclic organic compound of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate or building block for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs) and specialized organic materials.

Application

  • Pharmaceutical Intermediate: Key building block in the research and synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
  • Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
  • Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
  • Chemical Biology Probes: Utilized in the development of molecular probes for studying biological processes and target identification.
  • Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
  • Academic & Institutional Research: Employed in universities and research institutes for exploratory chemistry and the development of novel synthetic methodologies.

Basic Information

Product Name 2-[(1-Benzyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)Methyl]-3-(2-Methoxyphenyl)-4(3H)-Quinazolinone
CAS No. 371782-40-0
Molecular Formula C31H23N3O3
Molecular Weight 485.54 g/mol
Synonyms 3-(2-Methoxyphenyl)-2-[(1-benzyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-4(3H)-quinazolinone; 2-[(1-Benzyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-3-(2-methoxyphenyl)quinazolin-4(3H)-one; 371782-40-0; Quinazolinone derivative, benzyl indole substituted; A potential kinase inhibitor intermediate.
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Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client specifications. We support cGMP-compliant manufacturing for applications requiring the highest regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider under an inert atmosphere.

Specification

Item Specification
Appearance Yellow to orange crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0% (Area %)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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