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2-[(1-Benzyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)Methyl]-3-(2-Methoxyphenyl)-4(3H)-Quinazolinone CAS NO 371782-40-0
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CAS No.:371782-40-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-[(1-Benzyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)Methyl]-3-(2-Methoxyphenyl)-4(3H)-Quinazolinone is a high-purity, complex heterocyclic organic compound of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate or building block for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs) and specialized organic materials.
Application
- Pharmaceutical Intermediate: Key building block in the research and synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
- Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
- Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
- Chemical Biology Probes: Utilized in the development of molecular probes for studying biological processes and target identification.
- Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
- Academic & Institutional Research: Employed in universities and research institutes for exploratory chemistry and the development of novel synthetic methodologies.
Basic Information
| Product Name | 2-[(1-Benzyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)Methyl]-3-(2-Methoxyphenyl)-4(3H)-Quinazolinone |
| CAS No. | 371782-40-0 |
| Molecular Formula | C31H23N3O3 |
| Molecular Weight | 485.54 g/mol |
| Synonyms | 3-(2-Methoxyphenyl)-2-[(1-benzyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-4(3H)-quinazolinone; 2-[(1-Benzyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-3-(2-methoxyphenyl)quinazolin-4(3H)-one; 371782-40-0; Quinazolinone derivative, benzyl indole substituted; A potential kinase inhibitor intermediate. |
| EINECS | Contact for details |
Quality Control
Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client specifications. We support cGMP-compliant manufacturing for applications requiring the highest regulatory standards.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Yellow to orange crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 97.0% (Area %) |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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