Description

11-(2-Methyl-1H-Imidazol-1-Yl)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile is a high-purity, complex heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical research and development. Its intricate fused-ring structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying specific enzyme or receptor interactions in vitro.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized APIs under cGMP conditions.

Basic Information

Item	Details
Product Name	11-(2-Methyl-1H-Imidazol-1-Yl)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile
CAS No.	371211-70-0
Molecular Formula	C20H17N5
Molecular Weight	327.39 g/mol
Synonyms	11-(2-Methylimidazol-1-yl)-7,8,9,10-tetrahydrobenzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile; 371211-70-0; Benzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile, 7,8,9,10-tetrahydro-11-(2-methyl-1H-imidazol-1-yl)-; Tetrahydrobenzoimidazoisoquinoline carbonitrile derivative
EINECS	Contact for details

Quality Control

Our 11-(2-Methyl-1H-Imidazol-1-Yl)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.