Description

11-(Azepan-1-Yl)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile is a sophisticated heterocyclic organic compound featuring a fused polycyclic structure, making it a valuable advanced pharmaceutical intermediate and key building block in medicinal chemistry. Its unique molecular architecture is specifically designed for the synthesis of complex bioactive molecules, particularly in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas. This high-purity intermediate is essential for research institutions and pharmaceutical manufacturers engaged in developing novel small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those with complex polycyclic frameworks.
• Medicinal Chemistry Research: Used as a scaffold or building block in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• CNS Drug Development: Its structural features make it particularly relevant for research into compounds targeting neurological receptors and enzymes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	11-(Azepan-1-Yl)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile
CAS No.	371124-42-4
Molecular Formula	C22H24N4
Molecular Weight	344.46 g/mol
Synonyms	11-(1-Azepanyl)-7,8,9,10-tetrahydrobenzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile; Benzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile, 7,8,9,10-tetrahydro-11-(1-azepanyl)-; 371124-42-4; Tetrahydrobenzoimidazoisoquinoline carbonitrile derivative; Azepanyl-tetrahydrobenzoimidazoisoquinoline carbonitrile
EINECS	Contact for details

Quality Control

Our production of 11-(Azepan-1-Yl)-7,8,9,10-Tetrahydrobenzo[4,5]Imidazo[1,2-B]Isoquinoline-6-Carbonitrile adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided with every shipment. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.