Description

(3Ar,6Ar)-tert-Butyl Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate CAS NO 370882-39-6 is a high-purity, protected bicyclic pyrrolidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, nitrogen-containing scaffold that is essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing focused libraries in structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.
• Agrochemical Development: Serves as a building block for novel pesticides and herbicides requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(3Ar,6Ar)-tert-Butyl Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate
CAS No.	370882-39-6
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl (3aR,6aR)-Hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate; (3aR,6aR)-1-Boc-Octahydropyrrolo[3,4-b]pyrrole; (3aR,6aR)-N-Boc-2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-b]pyrrole; (3aR,6aR)-1-(tert-Butoxycarbonyl)octahydropyrrolo[3,4-b]pyrrole; (R,R)-1-Boc-2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-b]pyrrole; Bicyclic Pyrrolidine Boc-Protected Amine; Chiral Pyrrolidine Building Block
EINECS	Contact for details

Quality Control

Our (3Ar,6Ar)-tert-Butyl Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.