Description

2-Methoxy-5-Pyridineboronic Acid Hydrochloride is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in cross-coupling reactions, enabling the efficient construction of complex heterocyclic molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for constructing biaryl and heterobiaryl systems under mild conditions.
• Agrochemical Research: Used in developing new active ingredients for crop protection products.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Utilized as a tool compound for bioconjugation and probe development.
• Academic & Contract Research: A staple reagent in university and CRO laboratories for methodological development and library synthesis.

Basic Information

Product Name	2-Methoxy-5-Pyridineboronic Acid Hydrochloride
CAS No.	370864-57-6
Molecular Formula	C6H9BClNO3
Molecular Weight	189.41 g/mol
Synonyms	(5-Methoxy-2-pyridinyl)boronic acid hydrochloride; 2-Methoxy-5-pyridinylboronic acid HCl; 5-Methoxypyridine-2-boronic acid hydrochloride; (6-Methoxypyridin-3-yl)boronic acid hydrochloride; 2-Pyridineboronic acid, 5-methoxy-, hydrochloride; Boronic acid, B-(5-methoxy-2-pyridinyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-Pyridineboronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.