Description

1-Chloroisoquinolin-7-Yl-7-Boronic Acid is a high-value, multi-functional heterocyclic boronic acid derivative. This compound serves as a critical building block in modern synthetic organic chemistry, enabling the formation of carbon-carbon bonds via cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds. Its unique structure offers versatile functionalization potential for creating targeted libraries of compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers, due to its fused aromatic system.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Academic & Contract Research: Essential for methodological development in synthetic chemistry laboratories and for producing custom fine chemicals.

Basic Information

Product Name	1-Chloroisoquinolin-7-Yl-7-Boronic Acid
CAS No.	370864-49-6
Molecular Formula	C9H7BClNO2
Molecular Weight	207.42 g/mol
Synonyms	(7-Chloroisoquinolin-1-yl)boronic acid; 1-Chloro-7-isoquinolineboronic acid; 7-Chloro-1-isoquinolineboronic acid; 1-Chloro-7-isoquinolinylboronic acid; B-(7-Chloroisoquinolin-1-yl)boronic acid; 370864-49-6; 1-Chloroisoquinolin-7-ylboronic Acid
EINECS	Contact for details

Quality Control

Our 1-Chloroisoquinolin-7-Yl-7-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF Titration)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.