Description

1H-Indene-2,5-Diamine,2,3-Dihydro-,(2R)-(9Ci) is a chiral, diamine-substituted indane derivative of significant interest in advanced organic synthesis. This compound matters as a high-value, stereochemically defined building block for creating complex molecular architectures with specific three-dimensional orientations. Pharmaceutical research and development laboratories require it for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system and cardiovascular diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for neurological and cardiovascular targets.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize specialized ligands for transition metal catalysts in enantioselective synthesis.
• Advanced Material Monomer: Serves as a building block for high-performance polymers and resins with tailored thermal and mechanical properties.
• Agrochemical Research: Employed in the development of new chiral pesticides and herbicides where specific stereochemistry is crucial for activity.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry for constructing indane-based scaffolds.

Basic Information

Item	Detail
Product Name	1H-Indene-2,5-Diamine,2,3-Dihydro-,(2R)-(9Ci)
CAS No.	370861-69-1
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(2R)-2,3-Dihydro-1H-indene-2,5-diamine; (R)-2,3-Dihydro-1H-indene-2,5-diamine; (R)-Indan-2,5-diamine; (2R)-1H-Indene-2,5-diamine, 2,3-dihydro-; (R)-5-Aminoindan-2-amine; 370861-69-1; (R)-2-Amino-5-aminoindane; Chiral Indane Diamine
EINECS	Contact for details

Quality Control

Our 1H-Indene-2,5-Diamine,2,3-Dihydro-,(2R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its hygroscopic and oxidizable nature, containers must be kept tightly sealed after opening to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.