Description

2-(3,4-Dihydroxyphenyl)Ethyl-1-13C-Amine-15N Hcl is a stable isotope-labeled derivative of dopamine, specifically enriched with carbon-13 at the 1-position of the ethylamine side chain and nitrogen-15 at the amine nitrogen. This compound is essential for advanced analytical and research applications where precise molecular tracking and quantification are required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for use as an internal standard in mass spectrometry, metabolic pathway studies, and pharmacokinetic research.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in liquid chromatography-tandem mass spectrometry for the accurate analysis of dopamine and related catecholamines in complex biological matrices.
• Metabolic Tracer Studies: Used in stable isotope labeling experiments to investigate dopamine metabolism, neurotransmitter dynamics, and related biochemical pathways in vivo and in vitro.
• Pharmaceutical R&D: Employed in the development and validation of analytical methods for new drug candidates targeting the dopaminergic system.
• Clinical Research & Diagnostics: Facilitates precise measurement of neurotransmitter levels in clinical studies related to neurological disorders such as Parkinson's disease.
• Isotope Dilution Analysis: Enables high-precision quantification in environmental and food safety testing where dopamine or its analogs are analytes of interest.

Basic Information

Product Name	2-(3,4-Dihydroxyphenyl)Ethyl-1-13C-Amine-15N Hcl
CAS No.	369656-74-6
Molecular Formula	C8H12ClNO2 (with 13C and 15N isotopes at specified positions)
Molecular Weight	Contact for details
Synonyms	Dopamine-1-13C,15N Hydrochloride; 4-(2-Aminoethyl)benzene-1,2-diol-1-13C,15N hydrochloride; 3,4-Dihydroxyphenethylamine-1-13C,15N HCl; 3-Hydroxytyramine-1-13C,15N hydrochloride; DA-13C,15N HCl; [1-13C,15N]-Dopamine hydrochloride; Isotopically Labeled Dopamine HCl; 2-(3,4-Dihydroxyphenyl)ethyl-1-13C-amine-15N hydrochloride
EINECS	Contact for details

Quality Control

Every batch of our isotope-labeled compounds is produced and tested under strict quality management protocols. We guarantee high chemical and isotopic purity through rigorous analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific data for identity, purity (HPLC assay), isotopic enrichment, and residual solvent content. Our quality system supports compliance with cGMP and ISO standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Isotopic Enrichment (15N)	≥ 99 atom %
Chemical Purity (by 1H NMR)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.