Description

Propyl 2-(2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-Yl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate CAS NO 369399-59-7 is a high-purity, functionalized heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a maleimide and a tetrahydrobenzothiophene moiety, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and specialty chemical industries, particularly for applications requiring precise molecular conjugation or the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting neurological or oncological pathways.
• Bioconjugation Reagent: Utilized for site-specific labeling of proteins, antibodies, or peptides via the reactive maleimide group for diagnostics and targeted therapies.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce specific chemical handles into polymers for advanced material science.
• Agrochemical Research: Intermediate in the development of new active ingredients for crop protection with potential novel modes of action.
• Chemical Biology Probes: Used to create activity-based probes for studying enzyme function and protein interactions in complex biological systems.
• Ligand Synthesis: Building block for constructing complex ligands used in catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	Propyl 2-(2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-Yl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate
CAS No.	369399-59-7
Molecular Formula	C16H17NO4S
Molecular Weight	319.38 g/mol
Synonyms	1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2-(4,5,6,7-tetrahydro-3-benzothienyl) propyl ester; Propyl 2-(maleimido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 4,5,6,7-Tetrahydrobenzo[b]thiophene-3-carboxylic acid propyl ester, 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-; Maleimide-functionalized tetrahydrobenzothiophene propyl ester; 369399-59-7; Propyl 2-maleimido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Propyl 2-(2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-Yl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent batch-to-batch quality suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in the original packaging away from direct light and moisture sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.