Description

1-(Difluoro-Diphenyl-Phosphanyl-Methyl)-4-Dimethylamino-Pyridinium Triflate is a specialized organophosphorus salt, recognized as a highly effective and versatile reagent in modern synthetic chemistry. Its core value lies in its unique structure, which combines a phosphonium center with a dimethylaminopyridine moiety, making it an exceptional catalyst and ligand for a range of challenging transformations. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it facilitates the synthesis of complex molecules with high precision and efficiency.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex molecular scaffolds, particularly in the development of active pharmaceutical ingredients (APIs).
• Catalysis in Organic Synthesis: Functions as a potent catalyst or ligand in cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig amination.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific phosphorus-containing motifs.
• Advanced Material Development: Employed in the creation of specialized polymers, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new reaction pathways in academic and corporate research laboratories.
• Peptide Coupling & Modification: Can be utilized as an activating agent or catalyst in peptide synthesis and biomolecule conjugation.

Basic Information

Product Name	1-(Difluoro-Diphenyl-Phosphanyl-Methyl)-4-Dimethylamino-Pyridinium Triflate
CAS No.	368873-78-3
Molecular Formula	C21H21F5N2O3PS
Molecular Weight	507.43 g/mol
Synonyms	4-Dimethylaminopyridinium 1-(Difluorodiphenylphosphanyl)methyl Triflate; 1-[(Difluorodiphenylphosphino)methyl]-4-(dimethylamino)pyridinium Trifluoromethanesulfonate; (4-Dimethylaminopyridin-1-ium-1-ylmethyl)difluorodiphenylphosphonium Triflate; PDFA; DDFPPT; Phosphonium Salt Catalyst; Difluorophosphonium Pyridinium Salt
EINECS	Contact for details

Quality Control

Our production of 1-(Difluoro-Diphenyl-Phosphanyl-Methyl)-4-Dimethylamino-Pyridinium Triflate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and industrial applications. Each lot undergoes comprehensive analysis, including HPLC for assay and purity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.