Description

5-Methanesulfonyl-1H-Indole-2-Carboxylic Acid is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a methanesulfonyl group, makes it an indispensable precursor for creating complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and CNS disorders.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides that require specific indole-based scaffolds.
• Chemical Research: Serves as a versatile starting material for academic and industrial research in medicinal chemistry and material science.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-catalyzed reactions.
• Peptidomimetics: Incorporated into the design of peptide-like molecules to modulate biological pathways.

Basic Information

Product Name	5-Methanesulfonyl-1H-Indole-2-Carboxylic Acid
CAS No.	367501-41-5
Molecular Formula	C11H9NO4S
Molecular Weight	251.26 g/mol
Synonyms	5-(Methylsulfonyl)-1H-indole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 5-(methylsulfonyl)-; 5-Methanesulfonylindole-2-carboxylic acid; 5-Mesyl-1H-indole-2-carboxylic acid; 5-(Methanesulfonyl)indole-2-carboxylic acid; 367501-41-5; 5-Methylsulfonylindole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Methanesulfonyl-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. Our products are guaranteed to meet the high-purity standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.