Description

4-[(3-Methyl-2,4-Dioxo-1,3-Thiazolan-5-Yliden)Methyl]Benzenecarbonitrile is a high-value, specialized heterocyclic organic compound featuring a thiazolidinedione core linked to a benzonitrile moiety. This unique molecular architecture makes it a critical advanced intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams developing next-generation therapeutics and high-performance agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel thiazolidinedione-based drug candidates, particularly for metabolic and anti-inflammatory targets.
• Agrochemical Research: Used in developing new generations of herbicides and fungicides with specific modes of action.
• Material Science: Serves as a precursor for organic electronic materials, including semiconductors and light-emitting components.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic frameworks via its reactive methylidene and nitrile groups.
• Biochemical Probe Development: Utilized in creating molecular probes for studying biological pathways and enzyme inhibition.

Basic Information

Item	Detail
Product Name	4-[(3-Methyl-2,4-Dioxo-1,3-Thiazolan-5-Yliden)Methyl]Benzenecarbonitrile
CAS No.	367476-03-7
Molecular Formula	C12H8N2O2S
Molecular Weight	244.27 g/mol
Synonyms	5-[(4-Cyanobenzylidene)-3-methyl-2,4-thiazolidinedione; 3-Methyl-5-[(4-cyanophenyl)methylene]-2,4-thiazolidinedione; 4-[(3-Methyl-2,4-dioxo-5-thiazolidinylidene)methyl]benzonitrile; MCTD; 367476-03-7; Thiazolidinedione derivative; TZD derivative
EINECS	Contact for details

Quality Control

Every batch of our 4-[(3-Methyl-2,4-Dioxo-1,3-Thiazolan-5-Yliden)Methyl]Benzenecarbonitrile is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.