Description

4-Thiazolecarboxylicacid,2,5-Dihydro-2-Methyl-,Methylester,(2S)-(9Ci) is a chiral, non-racemic thiazole derivative, a crucial heterocyclic building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where its specific stereochemistry and functional groups enable precise molecular construction. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel, high-value compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the thiazole moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry, including cyclization reactions and heterocycle functionalization.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or conductive polymers due to the electron-rich thiazole ring system.

Basic Information

Product Name	4-Thiazolecarboxylicacid,2,5-Dihydro-2-Methyl-,Methylester,(2S)-(9Ci)
CAS No.	366806-84-0
Molecular Formula	C6H9NO2S
Molecular Weight	159.21 g/mol
Synonyms	(2S)-2,5-Dihydro-2-Methyl-4-Thiazolecarboxylic Acid Methyl Ester; Methyl (2S)-2-methyl-2,5-dihydro-1,3-thiazole-4-carboxylate; (S)-2-Methyl-2,5-dihydrothiazole-4-carboxylic acid methyl ester; (S)-Methyl 2-methyl-4,5-dihydrothiazole-4-carboxylate; 2,5-Dihydro-2-methyl-4-thiazolecarboxylic acid, methyl ester, (2S)-; 366806-84-0; (S)-2-Methyl-4,5-dihydrothiazole-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Thiazolecarboxylicacid,2,5-Dihydro-2-Methyl-,Methylester,(2S)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure consistent identity, purity, and enantiomeric excess suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated) for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.