Description

4-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Oxobutanoic Acid is a high-purity organic compound serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique molecular structure, featuring both a dihydroisoquinoline moiety and a carboxylic acid functional group, makes it a valuable building block for constructing complex molecules with potential biological activity. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and for method development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in custom synthesis and contract manufacturing.
• Academic & Institutional Research: Employed in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in API manufacturing.
• Ligand & Catalyst Development: Potential precursor for creating novel ligands used in asymmetric catalysis and metal-organic frameworks.

Basic Information

Product Name	4-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Oxobutanoic Acid
CAS No.	366454-59-3
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	4-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-4-oxobutanoic acid; 4-Oxo-4-(1,2,3,4-tetrahydro-2-isoquinolinyl)butanoic acid; 2-(3-Carboxypropionyl)-1,2,3,4-tetrahydroisoquinoline; Butanoic acid, 4-(1,2,3,4-tetrahydro-2-isoquinolinyl)-4-oxo-; 4-(3,4-Dihydro-2(1H)-isoquinolyl)-4-oxobutyric acid
EINECS	Contact for details

Quality Control

Our 4-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Oxobutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.