Description

Isoquinoline, 5-Chloro-6-Methoxy- CAS NO 366445-71-8 is a high-purity, functionalized isoquinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique heterocyclic structure, which provides a versatile scaffold for constructing complex molecules with targeted biological or material properties. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, catalyst development, and the synthesis of novel functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic core.
• Ligand and Catalyst Synthesis: Serves as a sophisticated ligand framework for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Building block for organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials where the isoquinoline moiety influences charge transport.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments requiring a stable, fused-ring structure for color fastness.
• Academic and Contract Research: Essential reagent for medicinal chemistry programs and methodological studies in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	Isoquinoline, 5-Chloro-6-Methoxy-
CAS No.	366445-71-8
Molecular Formula	C₁₀H₈ClNO
Molecular Weight	193.63 g/mol
Synonyms	5-Chloro-6-methoxyisoquinoline; 6-Methoxy-5-chloroisoquinoline; 5-Chloro-6-methoxy-isoquinoline; Isoquinoline, 5-chloro-6-methoxy-; 5-Chloro-6-methoxy-1-azanaphthalene
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-6-Methoxyisoquinoline is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.