Description

Ethyl 2-Amino-6-Cyano-1H-Indole-3-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical advanced intermediate in organic synthesis. This compound is valued for its versatile reactivity, particularly in constructing complex heterocyclic scaffolds and pharmaceutical active ingredients. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core structure.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing specialized polymers, dyes, and organic electronic materials.
• Academic & R&D: Essential for methodological studies in organic chemistry, heterocyclic chemistry, and medicinal chemistry research programs.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.

Basic Information

Product Name	Ethyl 2-Amino-6-Cyano-1H-Indole-3-Carboxylate
CAS No.	365548-02-3
Molecular Formula	C₁₂H₁₁N₃O₂
Molecular Weight	229.24 g/mol
Synonyms	2-Amino-6-cyano-1H-indole-3-carboxylic acid ethyl ester; Ethyl 2-amino-6-cyanoindole-3-carboxylate; 6-Cyano-2-aminoindole-3-carboxylic acid ethyl ester; 1H-Indole-3-carboxylic acid, 2-amino-6-cyano-, ethyl ester; 365548-02-3; EA6CIC; 2-Amino-6-cyanoindole-3-ethyl carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-6-Cyano-1H-Indole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.