Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, 3-Amino-, (1R,2R,3S,4S)- (9Ci) is a high-purity, stereochemically defined chiral building block with the CAS number 365544-86-1. This compound is valued for its rigid, functionalized norbornene scaffold, which is critical for constructing complex molecular architectures in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in asymmetric synthesis, medicinal chemistry, and the development of novel polymers and catalysts.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Employed in the design and synthesis of new-generation herbicides and pesticides with specific stereochemical requirements.
• Advanced Material Synthesis: Acts as a monomer or cross-linker for creating specialty polymers with unique thermal and mechanical properties.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its constrained geometry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, 3-Amino-, (1R,2R,3S,4S)- (9Ci)
CAS No.	365544-86-1
Molecular Formula	C8H12N2O
Molecular Weight	152.19 g/mol
Synonyms	(1R,2R,3S,4S)-3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxamide; (1R,2R,3S,4S)-3-Amino-2-norbornenecarboxamide; endo-3-Amino-2-norbornenecarboxamide; 3-Amino-2-norbornenecarboxamide (specific isomer); Bicyclo[2.2.1]hept-5-ene-2-carboxamide, 3-amino-, (1R-endo)-; 365544-86-1; Chiral Norbornene Carboxamide Derivative.
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, 3-Amino-, (1R,2R,3S,4S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.