Description

4-Bromo-1-Methyl-1H-Indazole is a versatile brominated indazole derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides due to its bioactive indazole core.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Ligand Synthesis: Utilized in organometallic chemistry for creating specialized ligands in catalytic systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	4-Bromo-1-Methyl-1H-Indazole
CAS No.	365427-30-1
Molecular Formula	C8H7BrN2
Molecular Weight	211.06 g/mol
Synonyms	1-Methyl-4-bromo-1H-indazole; 4-Bromo-1-methylindazole; 4-Bromo-1-methyl-1H-indazole; 1H-Indazole, 4-bromo-1-methyl-; 365427-30-1; 4-Br-1-Me-indazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methyl-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.