Description

2-Amino-5-Benzylthiophene-3-Carbonitrile is a high-value heterocyclic building block featuring both amino and nitrile functional groups on a thiophene scaffold. This compound is essential for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or building block for advanced polymers, organic semiconductors, and conductive materials due to the electron-rich thiophene core.
• Chemical Synthesis: Utilized in organic synthesis for constructing more complex fused-ring systems and heterocycles via reactions at the amino and nitrile groups.
• Dye and Pigment Intermediate: Acts as a starting material for the production of specialized dyes and organic pigments.

Basic Information

Product Name	2-Amino-5-Benzylthiophene-3-Carbonitrile
CAS No.	364596-21-4
Molecular Formula	C12H10N2S
Molecular Weight	214.29 g/mol
Synonyms	2-Amino-5-benzyl-3-thiophenecarbonitrile; 5-Benzyl-2-amino-3-cyanothiophene; 3-Cyano-5-benzyl-2-aminothiophene; 2-Amino-5-(phenylmethyl)thiophene-3-carbonitrile; 2-Amino-5-benzylthiophene-3-carbonitrile; 364596-21-4; 2-Amino-5-benzyl-3-thiophenenitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Benzylthiophene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) are provided with every shipment, detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.