Description

Bicyclo[3.2.1]Octane-3-Carboxylic Acid, 8-Amino-, Ethyl Ester, (3-Endo,8-Syn)- CAS NO 362656-63-1 is a high-purity, stereochemically defined bicyclic amino acid ester derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex molecules with precise three-dimensional architecture. It is essential for research and development in medicinal chemistry, particularly for organizations focused on novel drug discovery in therapeutic areas such as neurology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Peptidomimetics & Bioactive Molecule Synthesis: The rigid bicyclic scaffold is valuable for constructing conformationally restricted peptide analogs and other bioactive compounds.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical transformations.
• Chemical Biology Probes: Useful for creating molecular tools to study biological pathways and protein function.
• Academic & Industrial R&D: Serves as a specialty chemical for exploratory research in synthetic organic chemistry and drug discovery programs.

Basic Information

Item	Detail
Product Name	Bicyclo[3.2.1]Octane-3-Carboxylic Acid, 8-Amino-, Ethyl Ester, (3-Endo,8-Syn)-
CAS No.	362656-63-1
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	(3-endo,8-syn)-8-Aminobicyclo[3.2.1]octane-3-carboxylic acid ethyl ester; Ethyl (3-endo,8-syn)-8-aminobicyclo[3.2.1]octane-3-carboxylate; 8-Aminobicyclo[3.2.1]octane-3-carboxylic acid ethyl ester, endo,syn-; Bicyclo[3.2.1]octane-3-carboxylic acid, 8-amino-, ethyl ester, (3-endo,8-syn)-; 362656-63-1; Amino bicyclic ester; Chiral bicyclic amino ester
EINECS	Contact for details

Quality Control

Our production of Bicyclo[3.2.1]Octane-3-Carboxylic Acid, 8-Amino-, Ethyl Ester, (3-Endo,8-Syn)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.