Description

Acetyl-D3-L-Carnitine Hcl is a high-purity, isotopically labeled derivative of L-carnitine, specifically designed for research and development applications requiring precise metabolic tracing. This compound is critical for advanced studies in pharmacology, nutraceuticals, and metabolic research, where its deuterated structure provides a stable, non-radioactive tracer. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and manufacturers of high-end dietary supplements and diagnostic reagents.

Application

• Isotopic Tracer in Metabolic Research: Used as a stable, deuterium-labeled internal standard in mass spectrometry (LC-MS/MS, GC-MS) for quantifying L-carnitine and acetyl-L-carnitine in biological samples.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for method development, validation, and quality control in drug analysis and pharmacokinetic studies.
• Nutraceutical R&D: Employed in the research and development of advanced dietary supplements to study bioavailability, absorption, and metabolic pathways of carnitine derivatives.
• Diagnostic Reagent Manufacturing: A key component in the production of calibrators and controls for clinical diagnostic kits measuring carnitine levels.
• Biochemical Research: Used to investigate mitochondrial function, fatty acid metabolism, and energy production mechanisms in cellular and animal models.

Basic Information

Product Name	Acetyl-D3-L-Carnitine Hcl
CAS No.	362049-62-5
Molecular Formula	C9H15D3ClNO4
Molecular Weight	239.72 g/mol
Synonyms	(2R)-3-Carboxy-2-(acetyloxy)-N,N,N-trimethyl-1-propanaminium-2,3,3-d3 Chloride; Acetyl-D3-L-Carnitine Hydrochloride; L-Acetylcarnitine-d3 HCl; (R)-3-Acetoxy-4-(trimethylammonio-d3)butyrate Hydrochloride; Acetyl-D3-Levocarnitine Chloride; Stable Isotope Labeled Acetyl-L-Carnitine; ALCAR-d3 HCl; Deuterated Acetylcarnitine HCl
EINECS	Contact for details

Quality Control

Our Acetyl-D3-L-Carnitine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for chemical and isotopic purity, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for research and reference standard use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere or in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.