Description

Piperazine-D10 is a deuterated analog of piperazine, where ten hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This isotopic labeling is critical for applications requiring high chemical stability and minimal signal interference, such as in advanced analytical techniques. It is an essential building block and internal standard for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise molecular tracking and quantification.

Application

• Pharmaceutical Research & Development: Serves as a deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate bioanalysis and pharmacokinetic study of piperazine-containing drugs.
• Metabolic Pathway Tracing: Used in drug metabolism studies to track the fate of piperazine moieties within biological systems using Nuclear Magnetic Resonance (NMR) spectroscopy.
• Organic Synthesis Intermediate: Acts as a labeled precursor for synthesizing deuterated versions of complex molecules, including active pharmaceutical ingredients (APIs) and specialty chemicals, for research purposes.
• Analytical Reference Standard: Provides a certified reference material for calibrating analytical instruments and validating methods in quality control laboratories to ensure accuracy and compliance.
• Agrochemical Development: Employed in the synthesis and environmental fate studies of deuterated agrochemicals to understand degradation pathways and residue analysis.
• Material Science Research: Utilized in the development of novel polymers or materials where deuterium labeling helps in studying molecular structure, dynamics, and interactions via techniques like Neutron Scattering.

Basic Information

Product Name	Piperazine-D10
CAS No.	362049-61-4
Molecular Formula	C4D10N2
Molecular Weight	98.22 g/mol
Synonyms	Perdeuterated Piperazine; Piperazine-d10; 1,4-Diazacyclohexane-d10; Hexadeutero-piperazine; Deuterated Piperazine (D10); D10-Piperazine; 1,4-Diethylenediamine-d10; Piperazine (D10)
EINECS	Contact for details

Quality Control

Our Piperazine-D10 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and MS, to confirm isotopic purity and chemical identity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data for critical parameters such as isotopic enrichment and chemical purity. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (NMR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.