Description

2,6-Diaminotoluene-Alpha,Alpha,α-D3 is a deuterium-labeled isotopologue of 2,6-diaminotoluene, a key aromatic diamine intermediate. This labeled compound is essential for creating internal standards in mass spectrometry, enabling precise quantitative analysis and metabolic studies in pharmaceutical and agrochemical research. It is primarily utilized by analytical laboratories, research institutions, and manufacturers in the life sciences sector for applications requiring high isotopic purity and traceability.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in liquid chromatography-tandem mass spectrometry for analyzing its non-deuterated counterpart.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to track the absorption, distribution, metabolism, and excretion (ADME) of compounds derived from 2,6-diaminotoluene.
• Polymer Research: Acts as a labeled monomer or chain extender in the development and analysis of specialized polyurethanes and polyamides.
• Dye and Pigment Intermediate: Employed in the synthesis and quality control of deuterated dyes and pigments for research purposes.
• Pharmaceutical Impurity Profiling: Facilitates the accurate identification and quantification of process-related impurities and degradation products in active pharmaceutical ingredients (APIs).
• Environmental and Forensic Analysis: Enhances the accuracy of detection methods for toluene diamine isomers and their derivatives in complex matrices.

Basic Information

Product Name	2,6-Diaminotoluene-Alpha,Alpha,α-D3
CAS No.	362049-58-9
Molecular Formula	C7H7D3N2
Molecular Weight	125.18 g/mol
Synonyms	2,6-Diaminotoluene-d3; 2-Methyl-1,3-benzenediamine-d3; 2,6-Toluenediamine-d3; 2,6-Diamino-1-methylbenzene-d3; 1,3-Diamino-2-methylbenzene-d3; 2-Methyl-m-phenylenediamine-d3; Toluene-2,6-diamine-d3; 2,6-DAT-d3
EINECS	Contact for details

Quality Control

Our 2,6-Diaminotoluene-Alpha,Alpha,α-D3 is manufactured under controlled conditions to ensure high chemical and isotopic purity, critical for its use as an analytical standard. Each batch undergoes rigorous testing, including assay by HPLC, determination of isotopic enrichment by NMR or MS, and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.