Description

2-Chlorotoluene-3,4,5,6-D4 is a deuterated isotopologue of 2-chlorotoluene, where four hydrogen atoms are replaced with deuterium, a stable hydrogen isotope. This deuteration is critical for applications requiring non-radioactive isotopic labeling, such as in analytical chemistry and pharmaceutical research. It serves as an essential internal standard, tracer, or building block for scientists and manufacturers in pharmaceutical development, agrochemical research, and advanced material science where precise molecular tracking and mechanistic studies are paramount.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in GC-MS and LC-MS analysis due to its nearly identical chemical properties but distinct mass.
• Pharmaceutical Research & Metabolism Studies: Acts as a stable isotopic tracer to study the absorption, distribution, metabolism, and excretion (ADME) of drug candidates and related compounds.
• NMR Spectroscopy Solvent & Reagent: Employed as a deuterated solvent or reagent in Nuclear Magnetic Resonance (NMR) spectroscopy to avoid signal interference from protons.
• Mechanistic Reaction Studies: Utilized in chemical synthesis and catalysis research to elucidate reaction pathways and kinetic isotope effects.
• Agrochemical Development: Serves as a labeled intermediate in the synthesis and environmental fate studies of pesticides and herbicides.
• Material Science Research: Used in the development of specialty polymers and organic electronic materials where deuteration can alter physical properties.

Basic Information

Product Name	2-Chlorotoluene-3,4,5,6-D4
CAS No.	362049-57-8
Molecular Formula	C7H3D4Cl
Molecular Weight	131.61 g/mol (approx.)
Synonyms	2-Chloro-3,4,5,6-tetradeuteriotoluene; 1-Chloro-2-methyl-3,4,5,6-tetradeuteriobenzene; o-Chlorotoluene-d4; 2-Methylchlorobenzene-d4; Deuterated o-Chlorotoluene; (2-Chlorophenyl)methane-d4; 2-Chlorotoluene (phenyl-d4); Toluene-d4, 2-chloro-
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and tested under stringent quality protocols. Each batch of 2-Chlorotoluene-3,4,5,6-D4 is analyzed to ensure high chemical and isotopic purity, with specifications typically meeting the requirements for research and analytical applications. Certificates of Analysis (COA) detailing purity, isotopic enrichment (D atom %), and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use to prevent evaporation and concentration changes.

Specification

Item	Specification
Appearance	Clear Colorless Liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Isotopic Enrichment (D atom %)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.