Description

1,2-Dimethoxybenzene-D10 is a deuterated derivative of veratrole, where ten hydrogen atoms are replaced by deuterium, serving as a high-purity stable isotope-labeled internal standard. This compound is essential for ensuring analytical accuracy and reliability in quantitative mass spectrometry, eliminating matrix effects and signal variability. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, agrochemical, and environmental sectors for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of veratrole, its metabolites, and related compounds in complex biological matrices like plasma, urine, and tissue homogenates.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion (ADME) of parent compounds.
• Environmental Analysis: Employed as a reference standard in the detection and measurement of aromatic ether pollutants or degradation products in environmental samples.
• Synthetic Chemistry: Acts as a deuterated building block or precursor for the synthesis of more complex labeled compounds for mechanistic studies.
• Forensic Toxicology: Supports accurate quantification of specific analytes in forensic investigations requiring high evidentiary standards.
• Quality Control Laboratories: Ensures the accuracy and compliance of analytical methods within Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) environments.

Basic Information

Product Name	1,2-Dimethoxybenzene-D10
CAS No.	362049-43-2
Molecular Formula	C8D10O2
Molecular Weight	142.23 g/mol
Synonyms	Veratrole-d10; 1,2-Dimethoxybenzene-d10; 1,2-Dimethoxy(deuterobenzene); Deuterated Veratrole; Benzene-d5-1,2-dimethoxy-d5; Catechol Dimethyl Ether-d10; o-Dimethoxybenzene-d10
EINECS	Contact for details

Quality Control

Every batch of 1,2-Dimethoxybenzene-D10 is produced and analyzed under strict quality management protocols to ensure exceptional isotopic purity and chemical stability. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment (e.g., D10 ≥ 99 atom % D), chemical purity (by GC or HPLC), and specific analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong acids and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (D10)	≥ 99 atom % D (by 1H-NMR/MS)
Chemical Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.