Description

(+/-)-1,2-Dideutero-n-Trideuteromethyl-1-(3,4-Methylene-Dioxyphenyl)-2-Butanamine CAS NO 362043-98-9 is a high-purity, deuterated analog of a substituted phenethylamine, designed for advanced research and development applications. This compound is of significant value for its use as a stable isotope-labeled internal standard in analytical chemistry, enabling precise quantification and method validation. It is primarily needed by pharmaceutical R&D laboratories, forensic analysis teams, and academic institutions conducting metabolic, pharmacokinetic, and neurochemical studies.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical reference compound in LC-MS and GC-MS analysis for accurate quantification of its non-deuterated counterpart in complex biological matrices.
• Metabolic Pathway Tracing: Used in pharmacological and biochemical research to study drug metabolism, absorption, distribution, and excretion (ADME) due to its isotopic labeling.
• Forensic Toxicology: Employed as a certified reference material for the precise identification and measurement of controlled substances in forensic investigations.
• Neuropharmacology Research: Acts as a tool compound in studies investigating receptor binding, neurotransmitter activity, and the mechanisms of action of related psychoactive substances.
• Pharmaceutical Impurity Profiling: Aids in the development and validation of analytical methods to detect and quantify impurities and degradants in active pharmaceutical ingredient (API) batches.
• Isotope Dilution Analysis: Fundamental for high-accuracy analytical techniques that require the addition of a known quantity of an isotopically labeled analog to a sample.

Basic Information

Product Name	(+/-)-1,2-Dideutero-n-Trideuteromethyl-1-(3,4-Methylene-Dioxyphenyl)-2-Butanamine
CAS No.	362043-98-9
Molecular Formula	C12H11D5NO2
Molecular Weight	212.29 g/mol (average)
Synonyms	1-(1,3-Benzodioxol-5-yl)-2-(methyl-d3-amino)butane-1,2-d2; 3,4-Methylenedioxymethamphetamine-d5 (MDMA-d5); N-Methyl-d3-3,4-methylenedioxyamphetamine-1,2-d2; (±)-MDMA-d5; N-Methyl-3,4-methylenedioxyamphetamine-1,2-d2,N-methyl-d3; 1-(Benzo[d][1,3]dioxol-5-yl)-2-(methyl-d3-amino)butane-1,2-d2; 362043-98-9
EINECS	Contact for details

Quality Control

Every batch of our (+/-)-1,2-Dideutero-n-Trideuteromethyl-1-(3,4-Methylene-Dioxyphenyl)-2-Butanamine is produced and analyzed under strict quality management protocols to ensure the highest standards of isotopic purity and chemical identity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., argon or nitrogen) for long-term storage to prevent degradation. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (¹H, ¹³C, ²H)
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.