Description

D3-5α-Androstane-3α,17β-Diol is a high-purity steroidal diol derivative, serving as a critical intermediate and reference standard in advanced pharmaceutical research and development. Its defined stereochemistry and purity are essential for ensuring the accuracy and reproducibility of studies in endocrinology and metabolic pathways. This compound is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of novel therapeutic agents and analytical method development.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel steroidal drugs and hormone analogs.
• Reference Standard: Used for the calibration of analytical equipment (HPLC, GC-MS) and for qualitative and quantitative analysis in quality control laboratories.
• Biochemical Research: Employed in studies investigating androgen metabolism, enzyme activity (e.g., 5α-reductase), and related endocrine signaling pathways.
• Metabolite Standard: Serves as an analytical standard for the detection and quantification of steroidal metabolites in biological samples for clinical or forensic analysis.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, steroid biochemistry, and pharmacology.

Basic Information

Product Name	D3-5α-Androstane-3α,17β-Diol
CAS No.	361432-66-8
Molecular Formula	C19H32O2
Molecular Weight	292.46 g/mol
Synonyms	5α-Androstane-3α,17β-diol-d3; (3α,5α,17β)-Androstane-3,17-diol-d3; 3α,17β-Dihydroxy-5α-androstane-d3; Deuterated 5α-Androstanediol; D3-5α-Androstanediol; Androstanediol-d3; 5α-Adiol-d3; Isotopically Labeled Androstanediol
EINECS	Contact for details

Quality Control

Every batch of D3-5α-Androstane-3α,17β-Diol is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and isotopic enrichment meet the exacting requirements of research and development. A Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), isotopic purity, and related substance analysis is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (deuterium)	≥ 98 atom % D
Chemical Purity	≥ 95%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.