Description

D3-5α-Dihydrotestosterone CAS NO 361432-57-7 is a high-purity, synthetic steroid derivative of dihydrotestosterone (DHT), a potent endogenous androgen. This compound is of significant value in pharmaceutical research and development, serving as a critical reference standard and a key intermediate for the synthesis of novel therapeutic agents. It is primarily required by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in endocrinology, oncology, and metabolic disorder studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (e.g., HPLC, LC-MS) of related steroid compounds in drug development and quality control laboratories.
• Biochemical Research: Serves as a crucial tool for studying androgen receptor (AR) binding affinity, signal transduction pathways, and the physiological effects of DHT analogs.
• Active Pharmaceutical Ingredient (API) Intermediate: A key building block in the multi-step synthesis of advanced steroid-based pharmaceuticals targeting hormonal conditions.
• Metabolic Pathway Studies: Utilized in in vitro and in vivo models to investigate steroid metabolism, enzyme inhibition (5α-reductase), and related biochemical mechanisms.
• Development of Diagnostic Assays: Employed in the calibration and validation of immunoassays and other diagnostic kits designed to measure androgen levels.

Basic Information

Product Name	D3-5α-Dihydrotestosterone
CAS No.	361432-57-7
Molecular Formula	C19H27D3O2
Molecular Weight	293.46 g/mol
Synonyms	17β-Hydroxy-5α-androstan-3-one-d3; 5α-Dihydrotestosterone-d3; DHT-d3; Androstanolone-d3; 5α-DHT-d3; NSC 13768-d3; Stanolone-d3; (5α,17β)-17-Hydroxyandrostan-3-one-d3
EINECS	Contact for details

Quality Control

Every batch of D3-5α-Dihydrotestosterone is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic purity, and related substances are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.