Description

6-Chloro-8-Amino-β-Carboline is a high-purity, heterocyclic organic compound belonging to the β-carboline alkaloid class, serving as a critical synthetic intermediate and research chemical. Its value lies in its unique fused ring structure, which provides a versatile scaffold for developing novel pharmacologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors, particularly those focused on medicinal chemistry, neuroscience, and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new β-carboline derivatives with potential biological activity.
• Neuroscience Research: Investigated for its interactions with various neurotransmitter receptors, including benzodiazepine and serotonin receptors.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Biochemical Tool Compound: Utilized in vitro and in vivo studies to probe biological pathways and enzyme functions related to the β-carboline core.
• Academic & Industrial R&D: A fundamental material for organic synthesis and chemical research in university and corporate laboratories.

Basic Information

Product Name	6-Chloro-8-Amino-β-Carboline
CAS No.	361202-25-7
Molecular Formula	C₁₁H₈ClN₃
Molecular Weight	217.65 g/mol
Synonyms	8-Amino-6-chloro-β-carboline; 6-Chloro-8-amino-9H-pyrido[2,3-b]indole; 6-Chloro-8-β-carbolinamine; 6-Cl-8-NH2-βC; 361202-25-7; 6-Chloro-8-aminobetacarboline; 8-Amino-6-chloro-9H-pyrido[2,3-b]indole
EINECS	Contact for details

Quality Control

Our 6-Chloro-8-Amino-β-Carboline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.