Description

2-(5-Nitro-2-Thienyl)-1,3-Thiazolane-4-Carboxylic Acid is a specialized heterocyclic building block featuring a nitro-substituted thiophene ring fused to a thiazolidine carboxylic acid moiety. This compound matters as a key synthetic intermediate for the development of novel pharmaceuticals and advanced materials, offering a unique structural motif for creating molecules with targeted biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for drug discovery programs and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for creating functionalized polymers or organic electronic materials due to its conjugated thiophene system.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the study of enzyme inhibitors.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-(5-Nitro-2-Thienyl)-1,3-Thiazolane-4-Carboxylic Acid
CAS No.	360791-20-4
Molecular Formula	C8H8N2O4S2
Molecular Weight	260.29 g/mol
Synonyms	2-(5-Nitrothiophen-2-yl)-1,3-thiazolidine-4-carboxylic acid; 1,3-Thiazolidine-4-carboxylic acid, 2-(5-nitro-2-thienyl)-; 2-(5-Nitro-2-thienyl)thiazolidine-4-carboxylic acid; 2-(5-Nitrothien-2-yl)thiazolidine-4-carboxylic acid; 2-(5-Nitro-2-thienyl)-4-carboxy-1,3-thiazolidine; 360791-20-4; 2-(5-Nitro-thiophen-2-yl)-thiazolidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-(5-Nitro-2-Thienyl)-1,3-Thiazolane-4-Carboxylic Acid adheres to stringent in-process controls and final batch analysis to ensure consistent purity and identity. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, related substances, and residual solvents. We maintain a quality management system aligned with cGMP principles for active pharmaceutical ingredients (APIs), ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert gas purging to minimize potential degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.