Description

n-Ethyl-D5-Maleimide is a deuterated analog of N-ethylmaleimide, a versatile chemical building block and biochemical reagent. This deuterium-labeled compound is essential for applications requiring isotopic labeling, such as mass spectrometry-based proteomics and metabolic studies, where it provides enhanced detection sensitivity and accuracy. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for drug development, protein analysis, and as a reference standard.

Application

• Isotopic internal standard for quantitative mass spectrometry (LC-MS/MS) analysis.
• Biochemical research tool for studying protein structure, function, and thiol group modification.
• Deuterated precursor in the synthesis of labeled pharmaceutical compounds and metabolites.
• Use in proteomics for labeling and tracking biomolecules in complex biological samples.
• Reference material for analytical method development and validation in regulatory environments.
• Intermediate for synthesizing more complex deuterated organic molecules.

Basic Information

Product Name	n-Ethyl-D5-Maleimide
CAS No.	360768-37-2
Molecular Formula	C6D5NO2
Molecular Weight	140.16 g/mol
Synonyms	N-Ethyl-d5-maleimide; 2,5-D5-N-Ethylmaleimide; 1-(1,1,2,2,2-Pentadeuterioethyl)-1H-pyrrole-2,5-dione; Ethyl-d5-maleimide; NEM-d5; Deuterated N-Ethylmaleimide; N-Ethylmaleimide-d5
EINECS	Contact for details

Quality Control

Our n-Ethyl-D5-Maleimide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and isotopic enrichment, meeting the stringent requirements for research and analytical applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (by HPLC/NMR), isotopic purity (D-content), and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.