Description

tert-Butyl 4-((1-Oxoisoindolin-2-Yl)Methyl)Piperidine-1-Carboxylate CAS NO 359629-19-9 is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-isoindolinone hybrid structure. This compound is of significant value in medicinal chemistry for constructing complex molecular scaffolds, particularly in the development of targeted therapeutics. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the construction of linker and ligand components for bifunctional degrader molecules.
• Kinase Inhibitor Synthesis: Serves as a core structural element in the research and development of selective kinase inhibitors.
• Chemical Biology Research: Employed as a tool compound for studying protein-protein interactions and enzyme function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific novel chemical entities (NCEs).
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacology studies.

Basic Information

Product Name	tert-Butyl 4-((1-Oxoisoindolin-2-Yl)Methyl)Piperidine-1-Carboxylate
CAS No.	359629-19-9
Molecular Formula	C20H26N2O3
Molecular Weight	342.44 g/mol
Synonyms	1-Boc-4-((1-oxoisoindolin-2-yl)methyl)piperidine; 1-(tert-Butoxycarbonyl)-4-((1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl)piperidine; tert-Butyl 4-[(1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]piperidine-1-carboxylate; 2-[(1-Boc-4-piperidyl)methyl]isoindolin-1-one; 359629-19-9; 4-[(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((1-Oxoisoindolin-2-Yl)Methyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.