Description

(R,S)-n-Ethylnorcotinine is a synthetic nicotine analog and a key intermediate in advanced pharmaceutical research. This compound is of significant interest for its role in the development of novel therapeutics and diagnostic agents targeting nicotinic acetylcholine receptors. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, medicinal chemistry, and the development of smoking cessation aids or neurological disorder treatments.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates targeting the central nervous system.
• Neuropharmacology Research: Used as a reference standard or active compound in studies investigating nicotinic receptor function and modulation.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop selective receptor ligands.
• Metabolite Studies: Employed in analytical and bioanalytical research as a metabolite analog for pharmacokinetic and metabolic pathway investigations.
• Diagnostic Agent Development: Potential use in the development of radiolabeled tracers for positron emission tomography (PET) imaging.

Basic Information

Product Name	(R,S)-n-Ethylnorcotinine
CAS No.	359435-41-9
Molecular Formula	C11H16N2O
Molecular Weight	192.26 g/mol
Synonyms	N-Ethylnorcotinine; 1-Ethyl-5-(pyridin-3-yl)-2-pyrrolidinone; 3-[(2-Oxo-1-ethylpyrrolidin-3-yl)]pyridine; Norcotinine N-ethyl derivative; rac-N-Ethylnorcotinine; (±)-N-Ethylnorcotinine; DL-N-Ethylnorcotinine
EINECS	Contact for details

Quality Control

Our (R,S)-n-Ethylnorcotinine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.