Description

N,n-Di(Ethyl-2,2,2-D3)Aniline is a deuterated organic compound where the hydrogen atoms on the ethyl groups are replaced by deuterium (D), a stable isotope of hydrogen. This deuteration is critical for applications requiring enhanced molecular stability, precise spectroscopic analysis, and reduced metabolic interference. It serves as a valuable building block and analytical standard for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in drug discovery and development processes.

Application

• Pharmaceutical Research & Development: Used as a deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantitative analysis of metabolites and drug compounds.
• Drug Discovery: Employed as a deuterated synthon in the synthesis of deuterated drug candidates, a strategy to potentially improve pharmacokinetic profiles, metabolic stability, and patent life.
• Agrochemical Development: Serves as a key intermediate in the synthesis of deuterated pesticides and herbicides, where isotopic labeling aids in studying environmental fate and metabolic pathways.
• NMR Spectroscopy: Acts as a useful solvent or reagent in Nuclear Magnetic Resonance (NMR) spectroscopy due to its deuterium content, helping to eliminate interfering proton signals.
• Organic Electronics & Materials Science: Utilized in the synthesis of deuterated organic semiconductors and advanced polymers, where deuteration can influence charge transport and material lifetime.
• Mechanistic Studies: Applied in kinetic isotope effect (KIE) studies to investigate reaction mechanisms and pathways in organic and catalytic chemistry.

Basic Information

Product Name	N,n-Di(Ethyl-2,2,2-D3)Aniline
CAS No.	358731-12-1
Molecular Formula	C10D6H9N
Molecular Weight	155.24 g/mol
Synonyms	N,N-Bis(2,2,2-trideuteroethyl)aniline; N,N-Di(ethyl-d3)aniline; Aniline, N,N-bis(2,2,2-trideuteroethyl)-; d6-N,N-Diethylaniline; Deuterated N,N-Diethylaniline; N,N-Diethylaniline-d6; N-Ethyl-N-(2,2,2-trideuteroethyl)benzenamine; N,N-Di(trideuteroethyl)aniline
EINECS	Contact for details

Quality Control

Our N,n-Di(Ethyl-2,2,2-D3)Aniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC-MS, and HPLC, to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) detailing purity, deuterium content, and impurity profiles are provided and available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Deuterium Content (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.