Description

Etidronic Acid-D3 is a deuterated isotopologue of etidronic acid, a phosphonate compound widely recognized for its chelating and scale inhibition properties. This labeled version, with three deuterium atoms replacing hydrogen, is essential for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for use as an internal standard in mass spectrometry, metabolic studies, and the development of novel deuterated compounds.

Application

• Internal standard for the quantitative analysis of etidronic acid and related phosphonates via LC-MS (Liquid Chromatography-Mass Spectrometry) and GC-MS.
• Tracer compound in pharmacokinetic and metabolic studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of etidronic acid.
• Key starting material or intermediate in the synthesis of deuterium-labeled pharmaceutical agents for enhanced stability or metabolic profiling.
• Research reagent in material science for studying the mechanism of scale and corrosion inhibition in deuterated solvent systems.
• Reference standard in analytical method development and validation to ensure accuracy and regulatory compliance in quality control laboratories.
• Probe molecule in NMR (Nuclear Magnetic Resonance) spectroscopy studies due to the distinct properties of deuterium.

Basic Information

Product Name	Etidronic Acid-D3
CAS No.	358730-93-5
Molecular Formula	C2D3H5O7P2
Molecular Weight	208.05 g/mol (deuterated form)
Synonyms	(1-Hydroxy-D3-ethylidene)bisphosphonic Acid; Deuterated Etidronic Acid; Etidronate-D3; 1-Hydroxyethane-1,1-diyldiphosphonic Acid-D3; HEDP-D3; Dequest 2010-D3 (labeled analog); Didronel-D3 (labeled analog); Phosphonic Acid, P,P'-(1-Hydroxy-D3-ethylidene)bis-
EINECS	Contact for details

Quality Control

Our Etidronic Acid-D3 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and MS for isotopic enrichment verification and HPLC for chemical purity and impurity profiling. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on deuterium incorporation, purity, and residual solvents, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a desiccated environment after opening to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Deuterium Incorporation (NMR/MS)	≥ 98 atom % D
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.