Description

Benzenemethanethiol, 2-Fluoro-5-Methyl- (9Ci) is a specialized fluorinated thiol building block, identified by CAS number 357613-07-1, valued for its unique combination of a reactive thiol group and a fluorine substituent on an aromatic ring. This compound is critical for introducing sulfur and fluorine moieties into target molecules, enabling the fine-tuning of electronic properties, lipophilicity, and metabolic stability. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key intermediate in the synthesis of more complex chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly for incorporating fluorine atoms to enhance bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine and sulfur groups contribute to biological activity and environmental persistence profiles.
• Material Science Precursor: Acts as a monomer or functionalization agent in the creation of specialty polymers, coatings, and advanced materials with specific surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the preparation of novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Chemical Research: Utilized in academic and industrial R&D settings for exploring new reaction pathways and synthesizing complex, fluorinated organic molecules.
• Flavor & Fragrance Intermediate: Potentially used in the synthesis of high-value aroma chemicals, leveraging the thiol group which is common in many potent fragrance compounds.

Basic Information

Product Name	Benzenemethanethiol, 2-Fluoro-5-Methyl- (9Ci)
CAS No.	357613-07-1
Molecular Formula	C8H9FS
Molecular Weight	156.22 g/mol
Synonyms	2-Fluoro-5-methylbenzyl mercaptan; (2-Fluoro-5-methylphenyl)methanethiol; α-Mercapto-2-fluoro-5-methyltoluene; 2-Fluoro-5-methylbenzylthiol; 2-Fluoro-5-methyl-α-toluenethiol; 1-(2-Fluoro-5-methylphenyl)methanethiol; 2-Fluoro-5-methylbenzenemethanethiol
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanethiol, 2-Fluoro-5-Methyl- (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and industrial use. Our standard quality control includes comprehensive analytical testing such as GC, HPLC, NMR, and FTIR for identity confirmation and purity assessment. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters including assay, identity, and impurity profiles. We are committed to meeting the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its easily oxidized nature, minimize headspace and exposure to air after opening. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.