Description

4,7-Dihydro-1-Methyl-4,7-Ethano-2H-Isoindole CAS NO 357608-23-2 is a specialized bicyclic organic compound featuring a unique isoindole core structure, which serves as a valuable synthetic intermediate and building block in advanced organic chemistry. Its rigid, fused-ring system is prized for its ability to impart specific steric and electronic properties to target molecules, enabling the development of novel materials and active compounds. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical sectors, where precise molecular architecture is critical for function.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides and herbicides, leveraging its unique scaffold for bioactivity.
• Material Science Research: Serves as a monomer or precursor for creating specialty polymers and organic electronic materials with tailored properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to construct sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A crucial reagent for methodological studies in organic synthesis, including cycloaddition reactions and ring-forming transformations.
• Fine Chemical Production: Integral to the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	4,7-Dihydro-1-Methyl-4,7-Ethano-2H-Isoindole
CAS No.	357608-23-2
Molecular Formula	C11H13N
Molecular Weight	159.23 g/mol
Synonyms	1-Methyl-4,7-ethano-2H-isoindole-4,7(1H)-dihydro; 1-Methyl-4,7-dihydro-4,7-ethano-2H-isoindole; 1-Methyl-4,7-ethanoisoindole-4,7-dihydro; 1-Methyl-4,7-methanoisoindole-4,7-dihydro (common misnomer); 4,7-Ethano-1-methyl-4,7-dihydro-2H-isoindole; Bicyclo[2.2.1]hept-5-ene-2,3-dicarboximide derivative (related structure).
EINECS	Contact for details

Quality Control

Our production of 4,7-Dihydro-1-Methyl-4,7-Ethano-2H-Isoindole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.