Description

7-Bromo-1,2,3,4-Tetrahydro-3-Isoquinolinemethanol is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential central nervous system (CNS) active compounds and other therapeutic agents.
• Agrochemical Synthesis: Used in research for developing new herbicides, fungicides, or plant growth regulators with novel modes of action.
• Ligand and Catalyst Development: The isoquinoline scaffold can be functionalized to create novel chiral ligands for asymmetric catalysis.
• Material Science Research: Acts as a building block for organic electronic materials or specialty polymers due to its fused aromatic-bicyclic structure.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and exploring new chemical spaces.
• Custom Synthesis Projects: A starting point for bespoke chemical manufacturing services targeting specific client molecule requirements.

Basic Information

Product Name	7-Bromo-1,2,3,4-Tetrahydro-3-Isoquinolinemethanol
CAS No.	356780-61-5
Molecular Formula	C₁₀H₁₂BrNO
Molecular Weight	242.11 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydroisoquinoline-3-methanol; 3-Isoquinolinemethanol, 7-bromo-1,2,3,4-tetrahydro-; 7-Bromo-1,2,3,4-tetrahydro-3-isoquinolinecarbinol; (7-Bromo-3,4-dihydro-1H-isoquinolin-3-yl)methanol; 7-Bromo-1,2,3,4-tetrahydroisoquinolin-3-ylmethanol; 7-Bromo-THIQ-3-methanol
EINECS	Contact for details

Quality Control

Our 7-Bromo-1,2,3,4-Tetrahydro-3-Isoquinolinemethanol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.