Description

1H-Indole, 2,3-Dihydro-3-(4-Piperidinyl)- is a high-purity, advanced pharmaceutical intermediate belonging to the indole alkaloid class of compounds. Its unique fused heterocyclic structure makes it a critical building block for the synthesis of complex bioactive molecules. This compound is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes.
• CNS Drug Development: A valuable scaffold for creating compounds with potential activity on neurological receptors.
• Oncology Research: Employed in the design and synthesis of potential small-molecule inhibitors for cancer therapy.
• Chemical Biology: Utilized as a probe or tool compound to study biological processes and protein interactions.
• Process Chemistry: Acts as a starting material for scaling up the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1H-Indole, 2,3-Dihydro-3-(4-Piperidinyl)-
CAS No.	356073-00-2
Molecular Formula	C13H16N2
Molecular Weight	200.28 g/mol
Synonyms	3-(4-Piperidinyl)-2,3-dihydro-1H-indole; 3-(Piperidin-4-yl)indoline; 3-Piperidin-4-yl-indoline; 4-(2,3-Dihydro-1H-indol-3-yl)piperidine; Indoline, 3-(4-piperidinyl)-; 1H-Indole, 2,3-dihydro-3-(4-piperidinyl)-; 356073-00-2
EINECS	Contact for details

Quality Control

Our production of 1H-Indole, 2,3-Dihydro-3-(4-Piperidinyl)- adheres to stringent quality management systems to ensure batch-to-batch consistency and reliability. The material is manufactured and tested in facilities that follow cGMP (Current Good Manufacturing Practice) guidelines where applicable. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request. Our quality commitment ensures the material meets the exacting standards required for pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.