Description

Benzenemethanol, 2-Fluoro-α-2-Propynyl-, (Alphar)- (9Ci) is a specialized fluorinated organic compound with a unique propargylic alcohol structure attached to a fluorobenzene ring. This molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, where its distinct reactivity profile enables the construction of complex molecular frameworks. The compound's sensitivity necessitates expert handling and reliable supply chain management from a trusted manufacturer.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the introduction of fluorine atoms can significantly improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, leveraging the propargyl group for further functionalization.
• Material Science Research: Employed in the synthesis of specialty polymers or advanced organic materials that incorporate fluorinated aromatic units for specific electronic or surface properties.
• Chemical Biology Probes: Utilized to create tagged molecules or activity-based probes for studying enzyme mechanisms or biological pathways in research settings.

Basic Information

Product Name	Benzenemethanol, 2-Fluoro-α-2-Propynyl-, (Alphar)- (9Ci)
CAS No.	355806-87-0
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	2-Fluoro-α-(prop-2-yn-1-yl)benzenemethanol; (αR)-2-Fluoro-α-(2-propynyl)benzenemethanol; 1-(2-Fluorophenyl)-3-butyn-1-ol; (R)-1-(2-Fluorophenyl)but-3-yn-1-ol; Alphar-2-Fluoro-α-2-Propynyl-Benzyl Alcohol; 2-Fluorobenzyl alcohol, α-propargyl-, (R)-; Propargyl(2-fluorophenyl)methanol
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanol, 2-Fluoro-α-2-Propynyl-, (Alphar)- (9Ci) is produced under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Standard analytical techniques including HPLC, GC, NMR, and chiral analysis are employed to verify identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are available upon request, providing full traceability and batch-to-batch consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.