Description

3-Thiophenecarboxylic Acid, 2-[(3-Chloro-1-Oxopropyl)Amino]-4-Phenyl-, Ethyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its unique thiophene-based structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers and organic semiconductors for electronic applications.
• Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for metal-catalyzed reactions due to its potential chelating sites.

Basic Information

Product Name	3-Thiophenecarboxylic Acid, 2-[(3-Chloro-1-Oxopropyl)Amino]-4-Phenyl-, Ethyl Ester
CAS No.	355003-70-2
Molecular Formula	C16H16ClNO3S
Molecular Weight	337.82 g/mol
Synonyms	Ethyl 2-[(3-chloropropanoyl)amino]-4-phenylthiophene-3-carboxylate; 2-[(3-Chloro-1-oxopropyl)amino]-4-phenyl-3-thiophenecarboxylic acid ethyl ester; 4-Phenyl-2-[(3-chloro-1-oxopropyl)amino]thiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-[(3-chloro-1-oxopropyl)amino]-4-phenyl-, ethyl ester; CAS 355003-70-2
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxylic Acid, 2-[(3-Chloro-1-Oxopropyl)Amino]-4-Phenyl-, Ethyl Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.