Description

5-Amino-4-(2-Methoxy-Phenylcarbamoyl)-3-Methyl-Thiophene-2-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its complex molecular architecture, featuring both thiophene and phenylcarbamoyl moieties, makes it a versatile intermediate for constructing sophisticated chemical libraries. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a critical building block in medicinal chemistry for constructing diverse compound libraries via parallel or combinatorial synthesis.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as organic semiconductors or specialty polymers, due to its conjugated thiophene system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	5-Amino-4-(2-Methoxy-Phenylcarbamoyl)-3-Methyl-Thiophene-2-Carboxylic Acid Ethyl Ester
CAS No.	354561-74-3
Molecular Formula	C16H18N2O4S
Molecular Weight	334.39 g/mol
Synonyms	Ethyl 5-Amino-4-[(2-methoxyphenyl)carbamoyl]-3-methylthiophene-2-carboxylate; 5-Amino-3-methyl-4-[(2-methoxyphenyl)carbamoyl]thiophene-2-carboxylic Acid Ethyl Ester; 354561-74-3; Thiophene-2-carboxylic acid, 5-amino-4-[(2-methoxyphenyl)carbamoyl]-3-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 5-Amino-4-(2-Methoxy-Phenylcarbamoyl)-3-Methyl-Thiophene-2-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistent high quality and batch-to-batch reproducibility. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.