Description

8-Ethyl-2,5-Dihydro-3H-[1,2,4]Triazino[5,6-B]Indole-3-Thione is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Oncology Drug Development: Investigated for its potential role in creating compounds that inhibit specific cancer-related enzymes or pathways.
• CNS-Active Compound Synthesis: Employed in the research and development of potential treatments for neurological disorders.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological mechanisms and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	8-Ethyl-2,5-Dihydro-3H-[1,2,4]Triazino[5,6-B]Indole-3-Thione
CAS No.	354548-36-0
Molecular Formula	C12H11N3S
Molecular Weight	229.30 g/mol
Synonyms	8-Ethyl-2,5-dihydro-3H-[1,2,4]triazino[5,6-b]indole-3-thione; 8-Ethyl-2,3,5-trihydro-[1,2,4]triazino[5,6-b]indole-3-thione; 354548-36-0; 8-Ethyl-2,5-dihydro-3H-[1,2,4]triazino[5,6-b]indol-3-thione; 8-Ethyl-3H-[1,2,4]triazino[5,6-b]indole-3-thione, 2,5-dihydro-; SCHEMBL21805527; BCP24733
EINECS	Contact for details

Quality Control

Our 8-Ethyl-2,5-Dihydro-3H-[1,2,4]Triazino[5,6-B]Indole-3-Thione is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.